LU Jie

(Department of Neonatology, Nanyang Central Hospital, Nanyang 473000, China)

AbstractObjective 'To observe the effeets of Yinchen Wuling Syrup combined with probiotics on the improvementof clinical symptoms and rehabilitation process in neonatal jaundice. Methods 125 cases with neonatal jaundice wereselected and randomly divided into two groups using a random number table method. 62 cases in the control groupwere treated with conventional therapy and probiotic therapy, while 63 cases in the observation group were treatedwith Yinchen Wuling Syrup in combination with the conventional and probiotic therapy. The symptom recoveryprogress, improvement of serum bilirubin levels, changes in liver metabolic function, inflammatory response, andmedication safety between the two groups were compared. Results After treatment, the observation group had lowertime for skin yellow staining to subside, fever to subside, gastrointestinal discomfort to recover, and hospital staythan those in the control group, with statistically significant difference( P<0.05 ). After 3 and 7 d treatment, the levels of TBll, indireet bilirubin, ALT Y-GT, ALP, CRP, IL-6, 'TNF-a in the observation group were all lowerthan those in the control group ( P<0.05 ). 'The incidence of drug-related adverse reactions in the observation groupwas slightly higher than that in the control group, and the diference was not statistically significant ( P>0.05 ).Conclusion Yinchen Wuling Syrup combined with probiotics accelerate the recovery process of neonatal jaundice,reduee bilirubin levels , promote liver metabolic funetion recovery efectively, and have a higher drug safety.Keywords : neonatal jaundice; Yinchen Wuling Syrup; probiotics; clinical symptoms; rehabilitation process

DOI:10.19296/j.cnki.1008-2409.2024-02-035

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