QU Qianqian, LI Lingling

( Department of Gastrointestinal Surgery, Zhumadian Central Hospital, 

Zhumadian 463000, China)

Abstract Objective To observe the application effect of Accelerated Rehabilitation Surgery (ERAS) concept inextubation after pancreaticoduodenectomy and its impact on the rehabilitation process of patients. Methods 123 patients who underwent panereaticoduodenectomy were selected and divided into 2 groups, using a random numbertable method. The control group were received routine management, while the intervention group were implementedclinical management based onthe ERAS concept. The postoperative extubation status, improvement ofgastrointestinal funetion , nutritional status, postoperative recovery process, and incidence of related complicationswere compared between the two groups of patients, Results Under different clinical management modes, the intervention group had lower gastric tube removal time , drainage tube removal time , incidence of adverse events afteitube removal, and reintubation rate than the control group, showing a statistically significant difference ( P<0.05 ).The levels of gastrin (GAS), motilin (MLT), total serum protein (TP), serum albumin (ALB), and serumtransferrin(TRF') in the intervention group were higher than in the control group (P<0.05). The anal exhaust time,first bowel movement time, autonomous eating time, and hospital stay in the intervention group were lower than inthe control group (P<0.05). The incidence of related complications in the intervention group was lower than that inthe control group(P<0.05). Conclusion Based on the ERAS concept, implementing clinical management forpatients undergoing pancreaticoduodenectomy can improve their postoperative extubation status. reduce adverseevents of extubation and the risk of re intubation, promote the recovery of gastrointestinal funetion and nutritionalstatus, accelerate the postoperative recovery process, and reduce the risk of complications.

Keywords : pancreaticoduodenectomy; accelerate rehabilitation surgery; postoperative extubation; gastrointestinal function; rehabilitation process

DOI:10.19296/i.cnki.1008-2409.2024-04-018

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