颜承云:
男,金沙js3777入口检测药学院药剂药动教研室教授,沈阳药科大学药剂学专业博士研究生,日本京都药科大学生物药剂室博士后,美国俄亥俄州立大学药学院药剂室访问学者。
主要研究方向:1.药用新辅料应用及肿瘤靶向传递系统研究;2.难吸收药物黏膜吸收的研究。
主要科研成果:主持日本21st Century COE Program 1项;主持国家自然科学基金3项、主持区(省)自然基金4项、教育厅重点实验室课题1项;参与其它部、厅、局级项目多项;在国内外著名医药刊物上发表论文30余篇,其中第一作者SCI论文13篇;获得发明型专利1项;获市科技进步一等奖1项;出版专著1部。
代表论文:
1.Chengyun Yan*, Jiwei Gu,Yuan Zhang , Kailun Ma, Robert J. Lee.
Yuan Zhang. Efficient delivery of the Bcl-2 antisense oligonucleotide G3139 via nucleus-targeted aCD33-NKSN nanoparticles. INT J PHARMACEUT. 2022,
(625):122074.
2.Chengyun Yan*, Weiguo Shi, Jiwei Gu,Robert J. Lee, Yuan Zhang . Design of a Novel Nucleus-Targeted NLS-KALA-SA Nanocarrier to Delivery Poorly Water-Soluble Anti-Tumor Drug for Lung Cancer Treatment. J Pharm Sci. 2021, 110(6):2432-2441.
3.Chengyun Yan*, Robert J. Lee. Tat Tagged and Folate Modified N-succinyl-
chitosan (Tat-Suc-FA)Self-assembly Nanoparticle for Therapeutic Delivery
OGX-011 to A549 Cells. Mol. Pharmaceutics. 2017, 14 (6): 1898–1905
4.Chengyun Yan*,Jiwei Gu. Improved intestinal absorption of water-soluble drugs by acetylation of G2 PAMAM dendrimer nanocomplexes in rat. Drug Deliv.and Transl.Res. 2017, 7(3): 408- 415.
5.Cheng-yun Yan*, Akira Yamamoto. Synthesis of Tat tagged and folate modified N-succinyl-chitosanself-assembly nanoparticles as a novel gene vector. International Journal of Biological Macromolecules. 2015, (72) 751–756